Research we've funded

The Can Too Foundation raises funds for cancer research through our partnerships with major beneficiary Cure Cancer Australia Foundation, and our collaboration partner Cancer Council NSW.

Since 2005, we have funded over 145 individual cancer research grants through Cure Cancer Australia, and two major research projects through Cancer Council NSW.

Cure Cancer Australia

Cure Cancer Australia is the Can Too Foundation's major beneficiary. Since 2005, Can Too has supported 145 research grants for brilliant early-career researchers.

Cure Cancer Australia identifies, assesses and funds the research they believe has the best possible chance of finding a cure. Most importantly, they fund research for ALL cancer types and ALL areas of cancer research. Many of the researchers they have funded in the past are now leading experts in cancer research; including Professors Roger Reddel, Carolyn Mountford, Martin Tattersall AO, Robyn Ward, Michelle Haber and Andrew Biankin.

That’s why Cure Cancer Australia was founded in 1967, and that’s why today they’re more passionate than ever to play a part in funding a cure for every cancer, for every Australian.

See the list of researchers currently funded below.

For more info, visit www.curecancer.com.au

Cancer Council NSW

Cancer Council NSW funds more than a dozen new research grants every year. Thanks to their funded research into cancer prevention, treatment and management, more than 61,000 cancer deaths were averted between 1987 and 2007.

The research Cancer Council NSW support covers everything from the causes of cancer to new cancer treatments, and is funded through a rigorous process that makes sure they fund excellent work.

Together we are developing and delivering new fundraising programs in the health and fitness space that engage members of the community to take part in fitness events to encourage a healthy lifestyle while raising funds for cancer research. Our programs aim at encouraging people to take up or maintain exercise as part of a healthy lifestyle to reduce their chances of being diagnosed with cancer.

To read more on our partnership with Cancer Council NSW, click here or visit www.cancercouncil.com.au

2016 2015 2014 2013 2012 2011 2010 2009 2008 2007  2006

Complete list of cancer research grants funded by the Can Too Foundation

2017 cancer research grants

Name

Research Area

Lay title

Funded With

Profile

Prof Neil Watkins Osteosarcoma Exploiting a genetic pathway to treat bone sarcomas Cancer Council NSW  

Dr Phoebe Phillips

Pancreatic Cancer

Targeting proteins to improve the efficacy of pancreatic cancer treatment

Cancer Council NSW

 

Dr Camille Guillery

Blood Cancer

Using the immune system to recognise, attack and kill cancers of the blood

Cure Cancer Australia

 

Dr Gillian Gould

Smoking Prevention

Working to chaning smoking behaviour in aboriginal women

Cure Cancer Australia

 

Dr Natalia Castano-Rodriguez

Stomach Cancer

Cell destruction processes in stomach cancer

Cure Cancer Australia

 

Dr Rochelle D'Souza

Brain Cancer

Understanding tumour behaviours in adult brain cancer

Cure Cancer Australia

 

Dr Susan Woods

Cancer Genetics & Biology

Do Gremlin1 expressing fibroblasts drive tumourigenesis

Cure Cancer Australia

 

Dr Jyotsna Batra

Prostate Cancer

Biomarkers for prostate cancer

Cure Cancer Australia

 

Dr Zaklina Kovacevic

 

Molecular functions of the Iron Regulated Metastasis Suppressor, NDRG1 and its potential as a Molecular Target

Cure Cancer Australia

 

Dr Fernando de Souza Fonseca Guimaraes

Melanoma

Immunotherapy for melanoma

Cure Cancer Australia  

Dr Sumit Sahni

Pancreatic Cancer

Therapies for pancreatic cancer

Cure Cancer Australia

 

Dr Yuan Cao

Breast Cancer

Immunotherapy for breast cancer treatment

Cure Cancer Australia

 

Dr George Sharbeen

Pancreatic Cancer

Developing treatments for pancreatic cancer

Cure Cancer Australia

 

Dr Clare Slaney

Immunotherapy

Targeting the tumour microenvironment to enhance immunotherapy against cancer

Cure Cancer Australia

 

2016 cancer research grants

Name

Research Area

Lay title

Funded With

Profile

Prof Neil Watkins Osteosarcoma Exploiting a genetic pathway to treat bone sarcomas Cancer Council NSW View

Dr Phoebe Phillips

Pancreatic Cancer

Targeting proteins to improve the efficacy of pancreatic cancer treatment

Cancer Council NSW

View

Dr Dominik Beck 

Leukaemia

The role of long-non coding RNAs in Acute Myeloid Leukaemia

Cure Cancer Australia

View

Dr Laura Bray

Prostate Cancer

Dissecting the molecular and cellular mechanisms of angiogenesis and bone metastasis in a bioengineered microenvironment model of prostate cancer

Cure Cancer Australia

View

Dr Clare Slaney

Immunotherapy

Targeting the tumour microenvironment to enhance immunotherapy against cancer

Cure Cancer Australia

View

Dr Shweta Tikoo

Breast cancer

Targeting breast cancer metastasis: Delineating the role of “Perivascular Macrophages” in tumour cell metastasis

Cure Cancer Australia

View

Dr Susan Woods

Cancer Genetics & Biology

Do Gremlin1 expressing fibroblasts drive tumourigenesis?

Cure Cancer Australia

View

Dr Jyotsna Batra

 

Prostate cancer

Identifying the role of a novel gene in prostate cancer which may lead
to possible therapeutic targeting

Cure Cancer Australia

View

Dr Zaklina Kovacevic

 

Prostate Cancer

Targeting a protein involved in the spread and progression of prostate cancer as a possible treatment

Cure Cancer Australia

View

Dr Stephen Matarallo

Lymphoma

Developing an antibody vaccine to fight lymphoma

Cure Cancer Australia  View

Dr Bree Foley

Immunotherapy

Harnessing the immune system as a mode to treat cancer

Cure Cancer Australia

View

Dr Sophie Broughton

Cancer Genetics & Biology

Discovering the molecular basis of IL-3 receptor signalling

Cure Cancer Australia

View

2015 cancer research grants

Name

Research Area

Lay title

Co-funded by

Profile

Dr Bree Foley

Basic Science - Immunotherapy

Harnessing the immune system as a mode to treat cancer

 

 

Dr Fernando Guimaraes

Breast Cancer

Targeting specific factors produced by breast cancer tumours that control breast cancer spreading

 

 

Dr Jyotsna Batra

Prostate Cancer

Identifying the role of a novel gene in prostate cancer which may lead
to possible therapeutic targeting

 

 

Dr Stephen Mattarollo

Lymphoma

 Developing an antibody vaccine to fight lymphoma

 

 

Dr Zaklina Kovacevic

Prostate Cancer

Targeting a protein involved in the spread and progression of prostate cancer as a possible treatment

 

 

Dr Hui K. Gan

Basic Science

Examining whether antibodies against surface cellular receptors have biological and anti-cancer effects

 

 

Dr Jason Wong

Acute Myeloid Leukaemia

Exploring genetic mutations in acute myeloid leukaemia (AML)

 

 

Dr Jill Larsen

Lung Cancer

Identification of lung tumour specific changes that can be exploited as potential targets for drug development

 

 

Dr Kevin Knower

Breast Cancer

Investigating novel therapeutic targets and their function in breast cancer connective tissue

 

 

Dr Michael Doran

Bone Marrow – Stem Cell

Advancing the technology to grow bone marrow stem cells outside of the body in order to treat bone cancers

 

 

Dr Patsy Soon

Breast Cancer

Studying the role of molecules produced by cancer supporting cells in triple negative breast cancers

 

 

Dr Phillippa Taberlay

Tumour

Testing novel cancer therapies and the influence of genes for early intervention in prostate cancer

 

 

2014 cancer research grants

Name

Research Area

Lay title

Co-funded by

Profile

Dr Khatira Anwari

Basic Science

Targeting specific proteins in order to kill cancer cells

 

 

Dr Jyotsna Batra

Prostate Cancer

Investigating prostate cancer genetic variants and their potential to act as biomarkers

 

 

Dr Paul Beavis

Breast Cancer

Investigating the role and effectiveness of the immune system modifiers in the treatment of breast cancer

National Breast Cancer Foundation

 

Dr Maté Biro

Tumour

Identifying the underlying mechanisms that drive the invasive migration of cancer cells

 

 

Dr Michael Doran

Bone Marrow – Stem Cell

Advancing the technology to grow bone marrow stem cells outside of the body in order to treat bone cancers

 

 

Dr Hui Gan

Basic Science

Examining whether antibodies against surface cellular receptors have biological and anti-cancer effects

 

 

Dr Jessica Holien

Leukaemia

Designing novel therapeutic agents that target specific blood cancer cell proteins using molecular modelling

Leukaemia Foundation

 

Dr Ana Janic

Tumour

Studying the tumour suppression gene in order to understand more about how it protects from cancer

 

 

Dr Kevin Knower

Breast Cancer

Investigating novel therapeutic targets and their function in breast cancer connective tissue

 

 

Dr Christine Napier

Basic Science

Exploiting mutations in a gene that protects cancer cells against specific stresses for therapeutic outcomes

   

Dr Patsy Soon

Tumour

Testing novel cancer therapies and the influence of genes for early intervention in prostate cancer

   

Dr Jason Wong

Acute Myeloid Leukaemia

Exploring genetic mutations in acute myeloid leukaemia (AML)

   

Dr Nikola Bowden

Melanoma

Working towards personalised melanoma diagnosis and treatment programs

   

Dr Laurent Pangon

Colorectal

Identify the mechanism by which MCC protein represses the major colorectal cancer pathway and discover new ways to target colorectal carcinogenesis

   

Dr Richard Payne

Immunotherapy

Develop immunotherapeutic vaccine for a range of epithelial cancers including breast, colon, pancreas, prostate & rectum

   

Dr Antonia Pritchard

Immunotherapy

Identification of tumour specific protein changes that can be used for cancer vaccines

   

Dr Yu Zheng

Bone / Breast / Prostate

Investigating mechanisms of bone metastases in breast and prostate cancer

   

2013 cancer research grants

Name

Research Area

Lay title

Co-funded by

Profile

Dr Nikola Bowden

Melanoma

Working towards personalised melanoma diagnosis and treatment programs

 

 

Dr Liesel Fitzgerald

Prostate Cancer

Investigating novel biomarkers to distinguish degree of clinical prostate cancer risk

Prostate Cancer Foundation of Australia  

Dr Smitha Georgy

Oesophageal

Understanding triggers for potential tumour suppressors to improve osephageal cancer control

   

Dr Aparna Jayachandran

Melanoma

Investigating invasion & resistance mechanisms which may offer new strategies to prevent melanoma progression

   

Dr Kenneth Micklethwaite

Leukaemia / Lymphoma

Developing “off the shelf” tumour killing immune cells for leukaemia & lymphoma from normal donors

   

Dr Lisa Mielke

Colorectal

Understand tumour triggers & investigate interventions to prevent tumour formation & improve treatments of colon cancer

   

Dr Donia Moujalled

Molecular Biology

Understanding how a protein that causes cell death functions & assess its use as a novel therapeutic strategy in cancer

   

Dr Patricia Nunez da Costa

Colorectal / Liver

Investigating liver regeneration & cancer progression to improve colorectal cancer patient outcome & survival after liver resection

   

Dr Laurent Pangon

Colorectal

Identify the mechanism by which MCC protein represses the major colorectal cancer pathway and discover new ways to target colorectal carcinogenesis

   

Dr Kara Perrow

Breast Cancer

Develop & test novel targeted anti-cancer drugs that selectively ‘seek out & destroy’ breast cancer cells that possess certain markers of malignancy

   

Dr Antonia Pritchard

Immunotherapy

Identification of tumour specific protein changes that can be used for cancer vaccines

   

Dr Fatima Valdes-Mora

Breast Cancer

Understanding the basis of anti-hormone therapy resistance & development of combined therapies through epigenetic drugs

National Breast Cancer Foundation  

Dr Jason Waithman

Skin Cancer

Investigating immune response to melanoma

   

Dr Adrian Wiegmans

Breast Cancer

Understanding metastatic progression of aggressive breast cancer

   

Dr Yu Zheng

Bone / Breast / Prostate

Investigating mechanisms of bone metastases in breast and prostate cancer

   

Dr Emma Baker

Bone Cancer

Investigating epigenetic signatures of bone cancer

   

Dr Rose Boutros

Basic Science

Investigating cell duplication processes and their effects on cancer

   

Dr Viive Howell

Melanoma

Investigating new targets for the treatment of malignant melanoma

   

Dr Carolyn McNees

Basic science

Investigating the role of DNA & proteins in cancer

   

Dr Paul Neilsen

Sarcoma

Investigating a new approach to treatment of bone and soft tissue cancers (sarcoma)

   

Dr Phoebe Phillips

Pancreatic Cancer

Investigating cell survival in pancreatic cancer

   

Dr Christopher Scarlett

Pancreatic Cancer

Investigating new therapy for pancreatic cancer

   

Dr Daniel Speidel

Chemotherapy

Better understand the success and side effects of radiation and chemotherapy

   

2012 cancer research grants

Name

Research Area

Lay title

Co-funded by

Profile

Dr Rose Boutros

Basic Science

Protein modifications in cell duplication processes and their effects on cancer

 

 

Dr Megan Bywater

Leukaemia

Clinical trial of therapy for Leukaemia and lymphoma

Leukaemia Foundation Australia  

Dr Hamish Campbell

Basic Science

Investigating mechanisms which may prevent lymphoma and other tumours

   

Dr Vivien Chen

Not tumour stream specific

Investigating ways of reducing the tendency for blood clots to occur in cancer patients

   

Dr Jacqueline Donoghue

Brain Cancer

Novel agents that target proteins present in brain cancer

   

Dr Jason Dowling

Prostate Cancer

Reduce treatment side effects in prostate cancer by using MRI scans

Prostate Cancer Foundation Australia  

Dr David Gallego-Ortega

Breast Cancer

Investigating anti-estrogen therapy resistance in breast cancer

National Breast Cancer Foundation  

Dr Viive Howell

Melanoma

A random mutagenesis strategy for identification of new targets for the treatment of malignant melanoma

   

Dr Andy Hsu

Basic Science

Investigating immune cells in myeloma and bone marrow malignancy

   

Dr Justin Lees

Glioblastoma

Inhibition of glioblastoma invasion by novel dynamin ring stabilisers

   

Dr Carolyn McNees

Basic Science

Investigating the role of DNA & proteins in cancer

   

Dr Akira Nguyen

Breast Cancer

Investigating potential therapeutic targets against metastatic breast cancer

   

Dr Helen Pearson

Prostate Cancer

A novel route for therapeutic intervention in prostate cancer

   

Dr Phoebe Phillips

Pancreatic Cancer

Investigating cell survival in pancreatic cancer

   

Dr Rachael Rutkowski

Ovarian Cancer

Clinical trials design and drug therapies in ovarian cancer

   

Dr Christopher Scarlett

Pancreatic (upper GI cancer)

Investigating new therapy for pancreatic cancer

   

Dr Clare Yan Slaney

Breast Cancer

Blocking breast cancer immune responses in breast cancer and relationship to metastasis to bone

National Breast Cancer Foundation  

Dr Daniel Speidel

Chemotherapy

Better understand the success and side effects of radiation and chemotherapy

   

Dr Randy Suryadinata

Basic science

The role of gene protein products in tumour cell growth and suppression

   

Dr Jason Waithman

Skin (melanoma)

Investigating immune response to melanoma

   

2011 cancer research grants

Name

Research Area

Lay title

Co-funded by

Profile

Dr Katie Ashton

Melanoma

A genetic investigation of mutyh in melanoma development

 

 

Dr Jeremy David Henson

Lung Cancer

Alternatice lengthening of telomeres in lung cancer & patient outcome/diagnosis

   

Dr Liz Caldon

Breast Cancer

DNA damage checkpoints in cancer

National Breast Cancer Foundation  

Dr Heidi Hilton

Early malignant transformation

Early malignant transformation

   

Dr Steven Lane

Leukaemia

Treatment of blood diseases

Leukaemia Foundation of Australia  

Dr Caroline Ford

Ovarian Cancer

Targeting a new epigenetic therapy for ovarian cancer

   

Dr Luc Furic

Prostate Cancer

Targeting treatments for Prostate Cancer

Prostate Cancer Foundation Australia  

Dr Loretta Lau

Neuroblastoma

Telomere maintenance in neuroblastoma

   

Dr Xue Qin Yu

Prostate Cancer

Stage of care prevalence for Prostate Cancer

Prostate Cancer Australia Foundation  

Dr Jennifer Stone

Breast Cancer

Understanding mammographic density as a predictor of breast cancer risk

National Breast Cancer Foundation  

Dr Xiaomeng Zhang

Breast Cancer

Hippo tumour suppressor pathway in breast cancer

National Breast Cancer Foundation  

Dr David Zielger

Malignant gliomas

Anti-apoptotic signalling pathways in malignant gliomas

   

2010 cancer research grants

Name

Research Area

Lay title

Co-funded by

Profile

Dr Fares Al-Ejeh

Lung Carcinoma

Cancer treatment through “Target Creation Strategy”. Combining chemotherapy with the tumour-targeted delivery of internal radiotherapy

   

Dr Daniel Andrews

Regulate tumour

Lymphocyte receptors that regulate tumour development and therapy

   

Dr Gough Au

Control of malignant glioma

Using viruses to kill cancer cells

   

Dr Kerrilyn Diener

Development of microfluidic chips

Development of microfluidic chips to isolate peripheral blood cell populations in pancreatic cancer

   

Dr Nicole Haynes

Antibody-based immunotherapeutics

Engineering antibodies to kill cancer

   

Dr Christine Napier

ALT Telomere maintenance mechanism

Seeking to stop unlimited cell proliferation

   

Dr Hilda Pickett

Telomere trimming

Unlocking cancer cells’ secrets by studying telomeres (the protective structures at the ends of chromosomes)

   

Dr Patsy Soon

Breast Cancer

Stopping breast cancer in its tracks

   

Dr Shusuke Toden

Colorectal cancer

Can fish oil protect against bowel cancer?

   

Dr Guy Tsafnat

Breakdowns in genes happen and why genes switch off

Finding out why breakdowns in genes happen and why genes switch off

   

2009 cancer research grants

Name

Research Area

Lay title

Co-funded by

Profile

Dr Eleanor Ager

Bowel and liver cancer

The spread of cancer (metastasis) to the liver is the leading cause of death in patients with bowel cancer. This study will establish the role of RAS in the normal liver and in tumours and the mechanisms by which RAS blockade inhibits the growth and spread of tumours

   
Dr Amber Alsop Chronic Lymphocytic Leukaemia Chronic Lymphocytic leukaemia (CLL) is the most common form of leukaemia in adults in the Western World. Many patients develop resistance to current chemotherapies. The development of new therapies for these patients is hampered by the limited platforms for pre-clinical testing of new drugs or therapy regimens. Amber’s project proposes overcoming this by establishing a new model of CLL for the testing of therapies, thereby hastening the introduction of new therapies to the clinic    
Dr Vanessa Bonazzi Melanoma There are no truly effective therapies for secondary melanoma and current treatment regimens generally rely on non-selective cytotoxic drugs. Through this project we will identify several new genes involved in the development and progression of melanocytic tumours. This will shed to the light on some of the mechanisms behind the development of melanoma and point to potential molecular targets for future design of therapies to reduce melanoma    
Dr Ivan Ivetac Breast and ovarian cancer PIK3CA (a signalling enzyme) mutations are frequently found in a number of common tumours including breast, ovarian and colorectal cancers. Ivan’s team will use a new model created in their laboratory to understand the role of PIK3CA mutations in cancer development and design specific anti-cancer agents for this pathway    
Dr Jordane Malaterre Protecting children’s brains against side-effects of radiotherapy Up to 40% of treated young cancer patients suffer long term cognitive loss that manifests as lowered intelligence quotients, reduced learning and memory performance. Our objectives are: i) understand the biological processes of irradiation induced damage to the young brain and ii) evaluate therapeutic interventions in a brain focused irradiation model that help in reducing long-term radiation side-effects that will translate in children following radiotherapy    
Dr Phoebe Phillips Pancreatic Cancer This project studies the cells involved in the local tissue reaction around pancreatic cancer. These cells may determine the progression of cancer. Modulation of their behaviours may limit pancreatic cancer growth, thereby improving clinical outcome    
Dr Ulla Simanainen Prostate Cancer Glucocorticoid hormones act via glucocorticoid receptor (GR) and typically stop dividing cells from multiplying, and may directly restrict the growth of prostate including prostate cancer. Our research is looking at the role of reduced GR in early stage prostate cancer which may lead to the multiplication of prostate cells. This may create more options in treating advanced prostate cancer    

2008 cancer research grants

Name

Research Area

Lay title

Co-funded by

Profile

Professor Maurice Eisenbruch

 

Breast Cancer

Understanding barriers to effective cross-cultural communication about prognosis of metastatic breast and other cancers (Communicating Prognoses) More than a quarter of cancer patients in Australia are from culturally diverse backgrounds, and miscommunications can lead to delayed treatment and poorer prognoses. This study will explore how cultural differences influence communication between doctors, cancer specialists, and patients from Greek, Chinese and Arabic speaking backgrounds. The results will provide information that can be used to train doctors to be more responsive to cultural differences, to better meet the psychosocial needs to cancer patients, and ensure patient participation in decision making.

 

 

Dr Susan Fanayan

Understanding cancer behaviour using proteomic approaches

Significance of MAL2-MUC1 interactions and identification of other novel MAL2 binding partners in cancer by proteomic approaches (Breast Cancer) A major challenge in cancer research is the identification of novel tumour markers, which can improve our ability to accurately diagnose and predict disease and treatment outcomes. This study investigates the MAL2 and MUC1 genes: despite numerous reports of MAL2 overexpression in different cancers, little is known about how increased MAL2 expression may advantage cancer cells. We will investigate the significance of MAL2-MUC1 interactions in cancer, and attempt to identify other novel MAL2 partners to help us understand the significance of MAL2 overexpression in cancer

   

Dr Viive Howell

Ovarian Cancer

Ovarian surface epithelial carcinoma modelling mediated by Sleeping Beauty insertional mutagenesis (Ovarian Cancer) Ovarian epithelial cancer (OEC) is the most lethal of the gynaecological cancers. Activation of “Sleeping Beauty”, which causes random disruption of additional genes, will induce rapid tumour formation. Tumours will be collected for future research to identify these cancer-causing genes, with the goal of discovering new genes of OEC. This will lead to earlier diagnosis and better understanding of the causes of OEC

   

Dr Toby Hulf

Prostate cancer

Epigenetic deregulation of miRNAs in cancer (Prostate Cancer) miRNAs are molecules that regulate gene expression in many biological processes, including growth and differentiation, but the role miRNAs play in cancer is not clearly understood. This project aims to identify and characterise the miRNAs involved in epigenetic mechanisms by analysing the regulation of miRNAs in prostate cancer cells. It is expected that the results will advance our understanding of miRNA biology, and potentially generate novel targets for cancer therapeutics

   

Dr Hugh Morgan

Control mechanisms in cancer

The role of active demethylation in maintaining the differentiation status of cells (Understanding Gene Expression) Cancer can be caused by genetic mutations, or “epigenetic” changes that affect gene expression. Some genes become epigenetically silenced during development, while other genes become “un-silenced”. Epigenetic changes can allow cells to escape normal controls and lead to cancer. This project tests whether mechanisms in the embryo also occur during normal development, providing a basis for understanding dysregulation of epigenetics in the onset of cancer

   

Dr Ron Sluyter

Issues relating to blood clotting

The P2X7 receptor and microparticles in cancer-associated thromboembolism (Understanding Blood Clotting) Blood clotting is a serious and life-threatening complication in people with cancer. Improved knowledge about the processes contributing to cancer related clotting may lead to improved treatments, and increase the quality of life and the life-span of cancer patients. This study aims to identify the causes of clotting in cancer patients by investigating the influence of the P2X7 receptor on tumour derived microparticles

   

Dr Wayne Thomas

Brain Tumours

Identifying and inhibiting the mechanisms of MYCN activation in brain tumours (Brain Tumours) Brain cancer is a leading cause of death in children under 10 years of age, and medulloblastoma represents approximately 25% of childhood brain cancers. Our studies will focus on identifying and understanding the mechanism of activation of the oncogene MYCN in medulloblastoma. Understanding the nature of tumour development will lead to the development of novel pharmaceuticals

   

2007 cancer research grants

Name

Research Area

Lay title

Co-funded by

Profile

Dr Graham Ball

Structural studies of the DNA complexes of new anti-tumour agents to aid better drug design

Many drugs kill tumours by binding to DNA. A new group of DNA-binding drugs is emerging with good experimental antitumour activity that works by preventing cells from expressing their genes. We do not understand the details of the structure of these DNA-drug complexes, nor how they inhibit gene expression. In this work we are proposing to study the 3-dimensional structure of such complexes in solution by NMR spectroscopy (magnetic resonance), so as to aid better drug design in the future.

   

Dr Megan Fabbro

Regulation of cytokinesis by EPLIN, and actin-binding protein (Understanding Cell Division)

Cell division maintains the stability and integrity of our genome. Genomic instability can lead to cancer. Cytokinesis is the final stage of cell division and is a critical step in protecting genomic integrity. Megan and her team identified EPLIN as a new component of this process and it appears to function in cytokinesis. The aim of this project is to characterise the mechanisms of action of EPLIN in the final stages of cell division.

   

Dr Kirsten Hammond

The role of UVA in Skin Cancer

Skin cancer is caused by ultraviolet (UV) radiation in sunlight. UV is a potent cancer causing agent because it causes cells to become cancerous while simultaneously preventing the immune system from destroying them. UV light is made up of two spectra: UVA and UVB. This study investigates a new mechanism whereby UVA causes immune suppression. Understanding how this process occurs is critical to preventing it.

   

Dr Tao Liu

The role of class 111 histone deacetylase SIRT1 in neuroblastoma

Cancer is the second most common cause of childhood death. Neuroblastoma is the most common solid tum

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